PRF for Skin Health | Lococo Wellness Clinic

PRF for Skin

Autologous Platelet-Rich Fibrin (PRF) is prepared from a small sample of your own blood and applied to target areas to support tone, texture, and overall skin quality. No additives. No gels.

What is PRF?

PRF is a 100% autologous concentrate containing platelets and a fibrin scaffold. It is created with a gentle spin protocol that avoids anticoagulants and additives. The prepared material is used locally on areas of focus to encourage a healthy skin environment.

How it’s used for skin

  • Periorbital support (under-eye brightness and crepe texture)
  • Overall tone and fine-line softening
  • Texture and luminosity in cheeks, temples, and jawline
  • Post-procedure pairing (as advised) to support recovery

Research on PRF for Skin Health

Emerging studies show PRF can enhance collagen formation, elasticity, and tone—helping skin appear brighter, smoother, and more hydrated. The regenerative factors in PRF support your body’s intrinsic healing process to restore vitality and glow.

Collagen & Elasticity

Increased dermal thickness and fiber density have been documented following PRF, promoting a firmer, lifted appearance.

Hydration & Brightness

Improved hydration and smoother texture observed via better skin barrier function and microcirculation.

Fine Lines & Tone

Gradual softening of fine lines and more even tone, including delicate areas like the under-eye and perioral region.

Under-Eye Area

Reductions in crepiness and pigment with improved suppleness and brightness.

Mid-Face & Cheeks

Enhanced elasticity and firmness contribute to a refreshed contour.

Jawline, Neck & Décolletage

Support for collagen remodeling and smoothness across these regions.

Show References
  • Choukroun J, et al. Platelet-Rich Fibrin (PRF): An Autologous Biomaterial for Skin Rejuvenation. Aesthet Surg J. 2018.
  • Toffler M, et al. Clinical and Histologic Evaluation of PRF in Facial Rejuvenation. J Cosmet Dermatol. 2020.
  • Al-Maawi S, et al. The Biological Effect of Platelet-Rich Fibrin on Skin Tissue Regeneration. Int J Growth Factors Stem Cells Dent. 2019.

Areas commonly improved with PRF

  • Under-eye region (dark circles, hollows, crepe-like texture)
  • Cheeks and mid-face (tone, elasticity, firmness)
  • Nasolabial folds and marionette lines (softening of fine lines)
  • Forehead and perioral region (smoother texture and hydration)
  • Jawline and temples (collagen support and contour)
  • Neck and décolletage (enhanced tone and reduced crepiness)

Pre- and Post-Treatment Instructions

Pre-Treatment Instructions
  • Wash your face thoroughly before your appointment using a gentle, natural, unscented face wash.
  • Avoid makeup, exfoliants, retinoids, and acids for 24 hours before treatment.
  • Stay well-hydrated and eat a light meal prior to your appointment.
  • Avoid alcohol and smoking for 24 hours before your session.
  • Minimize sun exposure or tanning for 48 hours pre-treatment.
Aftercare Instructions
  • Avoid touching or applying products for the first 12 hours after treatment.
  • Use only a gentle, unscented moisturizer after 24 hours.
  • Avoid makeup for 24 hours post-treatment.
  • Do not use exfoliants, acids, or retinols for 5 days.
  • Avoid sun exposure, saunas, or heat for 48 hours.
  • Sleep with your head slightly elevated the first night to minimize swelling.
  • Expect mild redness, warmth, or tenderness for 24–72 hours.
  • Avoid strenuous exercise, swimming, or pools for 24 hours.
  • Stay well-hydrated and follow individualized guidance.

Why patients choose PRF

  • Preference for an autologous, additive-free approach
  • Interest in supporting collagen and elasticity
  • Focus on tone, texture, and periorbital brightness

Safety & screening

Suitability is determined at consultation. PRF is not performed over active infection, in uncontrolled bleeding disorders, or during pregnancy at treatment sites. Please tell your clinician about all medications, supplements, and recent procedures.

What to expect

After consultation, a small amount of blood is drawn and processed to create PRF. The PRF is applied to targeted areas using sterile technique. Sessions typically last 45–60 minutes. Mild redness or swelling can occur for 24–72 hours.

FAQs

Is PRF the same as PRP?

PRF is prepared without anticoagulants and forms a fibrin scaffold, which may offer a slower, more gradual release compared with PRP.

When will I notice changes?

Timelines vary. Many people notice a refreshed look within weeks, with further changes as sessions progress.

Can PRF be combined with other skin services?

Often, yes. Your plan can include pairing strategies and home care that align with your skin goals.

Book or ask a question

Curious if PRF is a fit for your skin goals? We’ll review your history and outline a personalized plan.

Educational notice: This page is for general information and does not replace individualized medical advice. PRF is provided under clinical delegation by licensed professionals.

© 2025 Lococo Wellness Clinic. All rights reserved.