PRF for Lichen Sclerosus
At Lococo Wellness Clinic, Platelet-Rich Fibrin (PRF) is offered as an assessment-led option to support vulvar skin comfort and tissue quality in lichen sclerosus. Care is individualized and informed by emerging research on regenerative therapies.
Book AppointmentWhat is PRF?
Platelet-Rich Fibrin (PRF) is created from a small sample of your own blood. Through a gentle spinning process, platelets, fibrin, and growth factors are concentrated into a matrix that can be applied to specific areas of concern. Because PRF comes entirely from your own blood, it is biocompatible and contains no additives or anticoagulants.
Research on PRF and Lichen Sclerosus
Emerging research has explored the use of autologous platelet concentrates such as PRF and PRP in lichen sclerosus to improve vulvar tissue quality, reduce discomfort, and enhance healing. Early clinical studies and case reports suggest:
- Improvement in itching, pain, and dryness scores following PRF or PRP application.
- Enhanced elasticity and hydration of vulvar tissue on physical examination.
- Histologic findings showing improved collagen organization and epithelial thickness.
- Potential reduction in inflammatory markers and restoration of normal skin texture.
While larger controlled trials are still needed, preliminary data indicate PRF may help regenerate healthy tissue architecture and improve local comfort in patients with lichen sclerosus.
- Behnia-Willison F, et al. Autologous Platelet-Rich Plasma for the Treatment of Vulvar Lichen Sclerosus: A Prospective Case Series. J Low Genit Tract Dis. 2016.
- Casabona F, et al. New Surgical Approach to Lichen Sclerosus: Use of Autologous Platelet-Rich Plasma and Fibrin Matrix. Plast Reconstr Surg Glob Open. 2017.
- Tedesco M, et al. Platelet-Rich Plasma in Vulvar Lichen Sclerosus: A Randomized Controlled Trial. Gynecol Obstet Invest. 2019.
Why patients explore PRF
- Desire to improve vulvar tissue texture and comfort
- Preference for autologous (self-derived) regenerative options
- Interest in evidence-informed, non-pharmaceutical approaches
Your PRF plan
- Typical schedule: one session per month for three months
- Maintenance: one to three sessions per year, depending on individual goals
- Care is reassessed at each visit and adjusted as needed
Safety and screening
We carefully review your health history to ensure PRF is appropriate. PRF is not performed in the presence of active infection, uncontrolled bleeding disorders, or if you are pregnant in the treatment area.
What to expect
After a brief intake and preparation, a small amount of blood is drawn and processed to create PRF. The PRF is then applied to the area of focus using sterile technique. The procedure typically takes 45–60 minutes, and you may return to normal activities soon after. Mild tenderness or swelling can occur for 24–72 hours.
Frequently asked questions
Is PRF the same as PRP?
No. PRF is prepared without added anticoagulants and forms a fibrin matrix. It is considered a gentler, slower-releasing autologous preparation that may provide longer support to surrounding tissues.
Can I continue my existing lichen sclerosus treatments?
Yes. PRF can be incorporated as a regenerative option alongside ongoing care plans, depending on your comfort and clinical assessment.
Who can receive PRF?
New and existing patients are welcome. Suitability is determined after reviewing your health history and ensuring PRF is appropriate for you.
Book or ask a question
If you’d like to explore whether PRF is right for you, our team can review your health history and discuss next steps.
Book Online (Jane) Call 905-664-8500